Cytoreductive HIPEC-Combined Surgery in Treatment of Advanced Ovarian Cancer

نویسندگان

چکیده

Background . Ovarian cancer ranks 5th in the structure of female oncological mortality Russian Federation, with a first-year post-diagnosis rate almost 35%. In 75% cases, ovarian is diagnosed at stages III—IV. The disease usually represents as peritoneal carcinomatosis regarded an advanced form that demands attention, which renders issue highly relevant. We present literature review and analysis combined treatment outcomes patients hospitalised Kuvatov Republican Clinical Hospital within period 2020—2021. Materials methods article reviews foreign national scientific literature, well reports case data on 18 treated Department Oncology Results discussion A complete cytoreductive surgery was performed 100% cases. cohort I, mean operation time 256 vs. 364 min, intraoperative blood loss — 1200 1050 mL, hospital stay 14.6 18.7 bed-days. Postoperative complications were 16.7 50% I II. 30-day 0 16.6% monitoring enrolment currently continues. Conclusion HIPEC procedure not radical measure can only achieve maximum efficacy if coupled cytoreduction. stage III—IV concurrent approach promising requires further in-depth research more robust statistics.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Intraoperative Chemotherapy in the Treatment of Advanced Epithelial Ovarian Cancer

Background/Aims. Intraperitoneal intraoperative hyperthermic chemotherapy (HIPEC) has been used in the treatment of ovarian cancer. The purpose of the study is to determine the efficacy of HIPEC after cytoreductive surgery in advanced ovarian cancer. Patients/Methods. From 2006 to 2010 patients with advanced ovarian cancer were enrolled in a prospective nonrandomized study to undergo cytoreduct...

متن کامل

Combined Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy for the Treatment of Advanced Ovarian Cancer

Ovarian cancer is the leading cause of death from gynecologic cancer and the fifth cause of cancer deaths in women in developed countries (Yancik, 1993; Cannistra, 1993). The number of deaths seems to increase the last few years. More than 70% of the patients with ovarian cancer have advanced disease at the time of initial diagnosis because they remain asymptomatic in early stages (Roberts, 199...

متن کامل

Cytoreductive surgery in ovarian cancer

As the overall prognosis for patients with ovarian cancer is poor, the management of this condition should be restricted to expert multi-disciplinary teams in gynaecological oncology. Apparent early stage ovarian cancer requires accurate and complete staging so that potential sites for metastases are not missed. Omitting adequate staging may have significant consequences including a negative im...

متن کامل

The role of cytoreductive surgery and HIPEC in epithelial ovarian cancer.

Epithelial ovarian cancer (EOC) is the most common cause of death from gynecological cancer in the Western world. The current standard treatment of these patients consists of cytoreduction and systemic chemotherapy. One of the most distinct features of EOC is the tendency to disseminate into the peritoneal cavity and remain confined to the peritoneum and intra-abdominal viscera. This makes it a...

متن کامل

Cytoreductive surgery for advanced ovarian cancer: quo vadis?

Two-thirds of women who are newly diagnosed with invasive epithelial ovarian cancer present with stage III or IV disease.The preferred initial treatment has traditionally consisted of primary surgical debulking followed by platinum-based chemotherapy. However, recent data suggesting comparable efficacy for neoadjuvant chemotherapy and interval debulking have challenged this conventional dogma. ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: ?????????? ???????? ? ?????????

سال: 2022

ISSN: ['2076-3093', '2307-0501']

DOI: https://doi.org/10.24060/2076-3093-2022-12-1-28-34